Is 4-Nitro-O-Phenylenediamine Sulfate safe in cosmetics?
4-Nitro-O-Phenylenediamine Sulfate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
MODERATE
Cosmetic Ingredient
4-Nitro-O-Phenylenediamine Sulfate
INCI: 4-NITRO-O-PHENYLENEDIAMINE SULFATE
4-Nitro-O-Phenylenediamine Sulfate (CAS 68239-82-7) is a cosmetic cosmetic ingredient functioning as Oxidative hair dye (salt form of parent compound 4-NOPD, CAS 99-56-9). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 68239-82-7 →
Function
Oxidative hair dye (salt form of parent compound 4-NOPD, CAS 99-56-9)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted; covered under same CIR assessment as parent compound
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 4-Nitro-O-Phenylenediamine Sulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
KR Korea MFDS Annex 2 (Restricted)
Category: Restricted. Max: 산화염모제에 2.0%. 기타 제품에는 사용금지
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Editorial summary
Preliminary editorial summary for 4-Nitro-O-Phenylenediamine Sulfate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
Chemical Function
Dye
Frequently Asked Questions
Is 4-Nitro-O-Phenylenediamine Sulfate allowed in the EU?
4-Nitro-O-Phenylenediamine Sulfate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Nitro-O-Phenylenediamine Sulfate do in cosmetics?
4-Nitro-O-Phenylenediamine Sulfate functions as: Oxidative hair dye (salt form of parent compound 4-NOPD, CAS 99-56-9). It is classified as a cosmetic ingredient in our database. CAS number: 68239-82-7.
Compliance Tools
Check 4-Nitro-O-Phenylenediamine Sulfate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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