Acid Blue 74 Aluminum Lake
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Acid Blue 74 Aluminum Lake. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 2400 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 1350 mg/kg bw/day | oral | swine | Subchronic | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | rat | Multigeneration Reproductive | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 7500 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 7500 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
Expert Verdict
Regulatory Flags
Frequently Asked Questions
Is Acid Blue 74 Aluminum Lake safe in cosmetics?
Acid Blue 74 Aluminum Lake has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Is Acid Blue 74 Aluminum Lake allowed in the EU?
Acid Blue 74 Aluminum Lake EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acid Blue 74 Aluminum Lake do in cosmetics?
Acid Blue 74 Aluminum Lake functions as: Dye. It is classified as a cosmetic ingredient in our database. CAS number: 16521-38-3.
What is the Margin of Safety for Acid Blue 74 Aluminum Lake?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Acid Blue 74 Aluminum Lake?
The NOAEL (No Observed Adverse Effect Level) for Acid Blue 74 Aluminum Lake is 2400 mg/kg bw/day based on a Chronic study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Acid Blue 74 Aluminum Lake compliance across multiple jurisdictions:
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