Acryloyloxypropyl Polysilsesquioxane

INCI: ACRYLOYLOXYPROPYL POLYSILSESQUIOXANE

CAS Number
1204591-17-2
Function
Nail conditioning agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR concluded safe in present practices of use and concentration (Final Report, Dec 2017)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not currently in commercial use per VCRP. Residual monomer content should be controlled via cGMP. If used in sprays, inhalation exposure assessed as non-significant due to particle size > 10 µm.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Acryloyloxypropyl Polysilsesquioxane safe in cosmetics?

Not currently in commercial use per VCRP. Residual monomer content should be controlled via cGMP. If used in sprays, inhalation exposure assessed as non-significant due to particle size > 10 µm. The EU classifies Acryloyloxypropyl Polysilsesquioxane as "permitted". Safety rating: GOOD.

Is Acryloyloxypropyl Polysilsesquioxane allowed in the EU?

Acryloyloxypropyl Polysilsesquioxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acryloyloxypropyl Polysilsesquioxane do in cosmetics?

Acryloyloxypropyl Polysilsesquioxane functions as: Nail conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 1204591-17-2.

What is the Margin of Safety for Acryloyloxypropyl Polysilsesquioxane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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