Adenosine Phosphate

INCI: ADENOSINE PHOSPHATE

CAS Number
61-19-8
Function
Skin Conditioning Agent – Miscellaneous
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted in cosmetics. CIR Panel concluded safe as used (Final Report, Sept 2020). Drug products containing AMP were withdrawn per 21 CFR 216.24 (not safe/effective as vasodilator), but this does not affect cosmetic use.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Used around eyes at up to 0.5%; aerosol use at up to 0.04%. Inhalation of aerosolized AMP can provoke dyspnea in asthmatics—relevant for spray formats.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Adenosine Phosphate safe in cosmetics?

Used around eyes at up to 0.5%; aerosol use at up to 0.04%. Inhalation of aerosolized AMP can provoke dyspnea in asthmatics—relevant for spray formats. The EU classifies Adenosine Phosphate as "permitted". Safety rating: GOOD.

Is Adenosine Phosphate allowed in the EU?

Adenosine Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Adenosine Phosphate do in cosmetics?

Adenosine Phosphate functions as: Skin Conditioning Agent – Miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: 61-19-8.

What is the Margin of Safety for Adenosine Phosphate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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