Is Acetylphytosphingosine safe in cosmetics?
Acetylphytosphingosine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Acetylphytosphingosine
INCI: ACETYLPHYTOSPHINGOSINE
Acetylphytosphingosine (CAS 111599-76-5 (Tetraacetylphytosphingosine)) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Hair Conditioning; ceramide precursor/sphingolipid derivative. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 111599-76-5 (Tetraacetylphytosphingosine) →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Hair Conditioning; ceramide precursor/sphingolipid derivative
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA. CIR reviewed ceramides as a class and concluded safe in present practices of use and concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetylphytosphingosine.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Acetylphytosphingosine.
Regulatory Flags
natural-origin
Frequently Asked Questions
Is Acetylphytosphingosine allowed in the EU?
Acetylphytosphingosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetylphytosphingosine do in cosmetics?
Acetylphytosphingosine functions as: Skin Conditioning, Hair Conditioning; ceramide precursor/sphingolipid derivative. It is classified as a cosmetic ingredient in our database. CAS number: 111599-76-5 (Tetraacetylphytosphingosine).
Compliance Tools
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ACETALDEHYDE
Moderate
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Fragrance
ACETOBACTER FERMENT EXTRACT FILTRATE
Good
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Deodorant
ACETOBACTER/ASPERGILLUS/LACTOBACILLUS/LEUCONOSTOC/PEDIOCOCCUS/SACCHAROMYCES/ZYGOSACCHAROMYCES/CITRUS UNSHIU FRUIT/CITRUS JAPONICA FRUIT/CITRUS JUNOS FRUIT/ APPLE FRUIT/BANANA FRUIT/PAPAYA FRUIT/ PYRUS SEROTINA FRUIT/ DIOSPYROS KAKI FRUIT/WATERMELON FRUIT/PEACH FRUIT/ PRUNUS MUME FRUIT/FIG FRUIT/CHAENOMELES SINENSIS FRUIT/ERIOBOTRYA JAPONICA FRUIT/APRICOT FRUIT/ ZIZYPHUS JUJUBA FRUIT/CUCURBITA MAXIMA FRUIT/CASTANEA CRENATA FRUIT/VITIS COIGNETIAE FRUIT/RASPBERRY FRUIT/MOMORDICA GROSVENORII FRUIT/LYCIUM CHINENSE FRUIT/GLYCINE MAX SEED/PHASEOLUS ANGULARIS SEED/CANAVALIA ENSIFORMIS SEED/RICE SEED/HORDEUM VULGARE SEED/COIX LACRYMA-JOBI MA-YUEN SEED/ECHINOCHLOA CRUS-GALLI SEED/SETARIA ITALICA SEED/MILLET SEED/HEMEROCALLIS FULVA FLOWER/CABBAGE LEAF/STEM/MORUS BOMBYCIS LEAF/PERILLA FRUTESCENS LEAF/IPOMOEA BATATAS ROOT/COLOCASIA ANTIQUORUM TUBER/DIOSCOREA BATATAS RHIZOME/IRIDEA LAMINARIOIDES/LAMINARIA JAPONICA/NEMACYSTUS DECIPIENS/UNDARIA PINNATIFIDA/RADISH ROOT/TURNIP ROOT/CARROT ROOT/ARCTIUM LAPPA ROOT/NELUMBO NUCIFERA RHIZOME/ONION BULB/LILIUM AURATUM BULB/LICORICE ROOT/SAGITTARIA TRIFOLIA ROOT/SESAME SEED/GINKGO BILOBA SEED/JUGLANS SUBCORDIFORMIS FRUIT/PANAX GINSENG SEED/ACTINIDIA POLYGAMA FRUIT/HYDNUM ERINACEUM FRUITING BODY/GRIFOLA FRONDOSA FRUITING BODY/PRUNUS SALICINA FRUIT/AKEBIA QUINATA FRUIT/CRATAEGUS CUNEATA FRUIT/CORNUS OFFICINALIS FRUIT/NEPHELIUM LONGANA FRUIT/HOUTTUYNIA CORDATA/ARTEMISIA PRINCEPS/SASA VEITCHII LEAF/GLECHOMA HEDERACEA/CHAMOMILLA RECUTITA FLOWER/EQUISETUM ARVENSE/CASSIA OBTUSIFOLIA SEED/TARAXACUM OFFICINALE/ISODON JAPONICUS/SAFFLOWER FLOWER/PLANTAGO ASIATICA/SMALLANTHUS SONCHIFOLIUS ROOT/GARLIC BULB/GINGER RHIZOME/BEET RHIZOME/POLYGONUM ODORATUM RHIZOME/TURMERIC RHIZOME/ACANTHOPANAX SIEBOLDIANUS ROOT/PINUS KORAIENSIS SEED/LENTINUS EDODES FRUITING BODY/AURICULARIA AURICULA/VITIS LABRUSCA FRUIT/HELIANTHUS TUBEROSUS TUBER FERMENT EXTRACT
Good
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Skin Conditioning
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