Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Must not be derived from bovine CNS tissue (21 CFR 700.27; EU TSE rules). Plant-derived sources such as yeast fermentation are standard. Part of CIR's comprehensive ceramide safety assessment.
Regulatory Flags
Frequently Asked Questions
Is Acetylphytosphingosine safe in cosmetics?
Must not be derived from bovine CNS tissue (21 CFR 700.27; EU TSE rules). Plant-derived sources such as yeast fermentation are standard. Part of CIR's comprehensive ceramide safety assessment. The EU classifies Acetylphytosphingosine as "permitted". Safety rating: EXCELLENT.
Is Acetylphytosphingosine allowed in the EU?
Acetylphytosphingosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetylphytosphingosine do in cosmetics?
Acetylphytosphingosine functions as: Skin Conditioning, Hair Conditioning; ceramide precursor/sphingolipid derivative. It is classified as a cosmetic ingredient in our database. CAS number: 111599-76-5 (Tetraacetylphytosphingosine).
What is the Margin of Safety for Acetylphytosphingosine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Acetylphytosphingosine compliance across multiple jurisdictions:
Related Ingredients
Is Acetylphytosphingosine in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Acetylphytosphingosine in your formulation.