Good Cosmetic Ingredient NOAEL Data

Allyl Cyclohexylpropionate

INCI: ALLYL CYCLOHEXYLPROPIONATE

CAS Number
2705-87-5
Function
Fragrance (perfuming agent)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for Allyl Cyclohexylpropionate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 50 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 125 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 100 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 50 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 125 mg/kg bw/day oral rat Chronic COSMOS_DB
dose_tested 100 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

IFRA standard applies; free allyl alcohol must be controlled; Annex III concentration and purity conditions must be met

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive eu_cosing_listed

Frequently Asked Questions

Is Allyl Cyclohexylpropionate safe in cosmetics?

IFRA standard applies; free allyl alcohol must be controlled; Annex III concentration and purity conditions must be met The EU classifies Allyl Cyclohexylpropionate as "restricted". Safety rating: GOOD. 6 toxicological study endpoint(s) are available in our database.

Is Allyl Cyclohexylpropionate allowed in the EU?

Allyl Cyclohexylpropionate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Allyl Cyclohexylpropionate do in cosmetics?

Allyl Cyclohexylpropionate functions as: Fragrance (perfuming agent). It is classified as a cosmetic ingredient in our database. CAS number: 2705-87-5.

What is the Margin of Safety for Allyl Cyclohexylpropionate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Allyl Cyclohexylpropionate?

The NOAEL (No Observed Adverse Effect Level) for Allyl Cyclohexylpropionate is 50 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 6 study endpoints are available. Source: COSMOS_DB.

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