Aloesin

INCI: ALOESIN

CAS Number
30861-27-9
Function
Skin conditioning; UV-absorbing/skin-lightening properties (tyrosinase inhibitor)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no FDA restriction as cosmetic ingredient; not reviewed by CIR as standalone

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Lightening agent requiring careful concentration control; ensure no hydroquinone contamination from aloe processing, similar to arbutin concerns.

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Concern Level: Low

Frequently Asked Questions

Is Aloesin safe in cosmetics?

Lightening agent requiring careful concentration control; ensure no hydroquinone contamination from aloe processing, similar to arbutin concerns. The EU classifies Aloesin as "permitted". Safety rating: GOOD.

Is Aloesin allowed in the EU?

Aloesin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aloesin do in cosmetics?

Aloesin functions as: Skin conditioning; UV-absorbing/skin-lightening properties (tyrosinase inhibitor). It is classified as a cosmetic ingredient in our database. CAS number: 30861-27-9.

What is the Margin of Safety for Aloesin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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