Is Aloesin safe in cosmetics?
Aloesin has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Aloesin
Also known as: Aloe resin B, Aloeresin B, NSC 631262, UNII-Y27M69Y8ES
INCI: ALOESIN
Aloesin (CAS 30861-27-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning; UV-absorbing/skin-lightening properties (tyrosinase. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 30861-27-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning; UV-absorbing/skin-lightening properties (tyrosinase inhibitor)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
7-hydroxy-5-methyl-2-(2-oxopropyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
InChIKey
HKIKAXXIWJHWLY-ZIIYPAMZSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no FDA restriction as cosmetic ingredient; not reviewed by CIR as standalone
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Aloesin.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Aloesin.
Known Synonyms
Aloe resin B
Aloeresin B
NSC 631262
UNII-Y27M69Y8ES
Chemical Function
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL5172191
Frequently Asked Questions
Is Aloesin allowed in the EU?
Aloesin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Aloesin do in cosmetics?
Aloesin functions as: Skin conditioning; UV-absorbing/skin-lightening properties (tyrosinase inhibitor). It is classified as a cosmetic ingredient in our database. CAS number: 30861-27-9.
Is Aloesin used outside cosmetics?
Aloesin also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Aloesin compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Fragrance
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