Alpha-Santalyl Butyrate

INCI: ALPHA-SANTALYL BUTYRATE

CAS Number
67633-99-2
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted by FDA; permitted under general fragrance provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydrolysis product alpha-santalol is a known sensitizer, but the ester itself is not classified as sensitizing. EFSA concluded santalyl esters do not raise genotoxicity concerns.

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Alpha-Santalyl Butyrate safe in cosmetics?

Hydrolysis product alpha-santalol is a known sensitizer, but the ester itself is not classified as sensitizing. EFSA concluded santalyl esters do not raise genotoxicity concerns. The EU classifies Alpha-Santalyl Butyrate as "permitted". Safety rating: GOOD.

Is Alpha-Santalyl Butyrate allowed in the EU?

Alpha-Santalyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Alpha-Santalyl Butyrate do in cosmetics?

Alpha-Santalyl Butyrate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 67633-99-2.

What is the Margin of Safety for Alpha-Santalyl Butyrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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