Moderate Cosmetic Ingredient GHS Classified

Aluminum Fluoride

INCI: ALUMINUM FLUORIDE

CAS Number
7784-18-1
Function
Oral care agent (anticaries)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
EU Max Conc. 0.15%
🇺🇸 US Status restricted
US Notes Fluoride compounds in OTC anticaries products regulated under 21 CFR 355; aluminum fluoride is not among the FDA-listed monograph actives (sodium fluoride, stannous fluoride, and sodium monofluorophosphate are the approved actives)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The aerosol is irritating to the eyes, skin and respiratory tract.
Long-term Exposure Effects
Repeated or prolonged inhalation may cause asthma. The substance may have effects on the bone and central nervous system. This may result in bone alterations (fluorosis) and nervous system impairment.
Routes of Exposure
The substance can be absorbed into the body by inhalation of dust and by ingestion.

Expert Verdict

Prohibited in EU due to fluorosis risk in children; not approved as an active ingredient in US OTC anticaries products. Aluminum-fluoride complexes may affect fluoride bioavailability and require supervision in pediatric use.

⚠️
Concern Level: Moderate

Regulatory Flags

endocrine_disruptor eu_cosing_listed

Frequently Asked Questions

Is Aluminum Fluoride safe in cosmetics?

Prohibited in EU due to fluorosis risk in children; not approved as an active ingredient in US OTC anticaries products. Aluminum-fluoride complexes may affect fluoride bioavailability and require supervision in pediatric use. The EU classifies Aluminum Fluoride as "prohibited". Safety rating: MODERATE.

Is Aluminum Fluoride allowed in the EU?

Aluminum Fluoride EU regulatory status: prohibited. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.

What does Aluminum Fluoride do in cosmetics?

Aluminum Fluoride functions as: Oral care agent (anticaries). It is classified as a cosmetic ingredient in our database. CAS number: 7784-18-1.

What is the Margin of Safety for Aluminum Fluoride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Aluminum Fluoride compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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