Moderate Cosmetic Ingredient NOAEL Data

Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate

INCI: ALUMINUM HYDROXY BIS(2,2'-METHYLENE BIS(4,6-DI-T-BUTYLPHENYL))PHOSPHATE

CAS Number
151841-65-5
Function
Skin protectant, viscosity controlling agent, crystal growth inhibitor
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA UNII: 32S296KGN1; no specific CIR safety assessment published; limited cosmetic use data

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 50 mg/kg bw/day oral rat Subchronic COSMOS_DB
LOAEL 150 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Limited cosmetic safety dossier; if used in cosmetics, a full SCCS-type safety assessment would be recommended; primarily an industrial additive rather than a traditional cosmetic ingredient

โš ๏ธ
Concern Level: Moderate

Frequently Asked Questions

Is Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate safe in cosmetics?

Limited cosmetic safety dossier; if used in cosmetics, a full SCCS-type safety assessment would be recommended; primarily an industrial additive rather than a traditional cosmetic ingredient The EU classifies Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate allowed in the EU?

Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate do in cosmetics?

Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate functions as: Skin protectant, viscosity controlling agent, crystal growth inhibitor. It is classified as a cosmetic ingredient in our database. CAS number: 151841-65-5.

What is the Margin of Safety for Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate?

The NOAEL (No Observed Adverse Effect Level) for Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate is 50 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Aluminum Hydroxy Bis-Methylene Bis-Di-T-Butylphenyl Phosphate in your formulation.