Is Aluminum Lactate safe in cosmetics?
Aluminum Lactate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.
Aluminum Lactate
Also known as: Propanoic acid, 2-hydroxy-, aluminum complex, Aluminum, tris(2-hydroxypropanoate-O1,O2)-, Aluminum, tris(2-hydroxypropanoato-O1,O2)-, aluminum tris(alpha-hydroxypropionate), Aluminum, tris(2-(hydroxy-kappaO)propanoato-kappaO)- (+11 more)
INCI: ALUMINUM LACTATE
Aluminum Lactate (CAS 18917-91-4) is a cosmetic cosmetic ingredient functioning as Astringent, buffering agent, antimicrobial. NOAEL 0.18 mg/kg bw/day (primary-source verified against the SCCS opinion); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 18917-91-4 →
Function
Astringent, buffering agent, antimicrobial
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
bis(2-hydroxypropanoyloxy)alumanyl 2-hydroxypropanoate
InChIKey
VXYADVIJALMOEQ-UHFFFAOYSA-K
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
FDA-recognized topical astringent; also used in OTC drugs
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Aluminum Lactate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Aluminum Lactate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =10 mg/kg bw/day | oral: feed | Mouse | reproduction toxicity | EFSA |
| NOAEL | =10 mg/kg bw/day | oral: feed | Mouse | reproduction toxicity | EFSA |
Pre-Calculated Safety Assessment
Conditional — safe only within SCCS limits: aluminium assessed as AGGREGATE systemic exposure, not per-compound (SCCS/1644/22 Table 18): all cosmetic routes summed = 0.80 ug Al/kg/day vs POD 180 ug/kg/day = MoS 225; safe in all cosmetic categories at maximum use-levels (Tables 4/6); aerosol sprays require under 20% of particles below 10 um
Pre-calculated NOAEL → SED → MoS audit trail for Aluminum Lactate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
Not listed by IARC. IARC classified aluminum production as carcinogenic to humans (Group 1), but did not implicate aluminum itself as a human carcinogen. (L135) A link between use of aluminum-containing antiperspirants and increased risk of breast cancer has been proposed (A235), but studies have not been able to establish a clear link (A15468).
Source: Toxin and Toxin Target Database (T3DB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Astringent
Deodorizer
pH regulating agent
Editorial summary
Preliminary editorial summary for Aluminum Lactate — not a computed safety verdict. See the sourced toxicological data above.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Aluminum Lactate by CAS number or substance name.
Studies
2
Lowest NOAEL
10 mg/kg bw/day
Highest NOAEL
10 mg/kg bw/day
EFSA
Known Synonyms
Propanoic acid, 2-hydroxy-, aluminum complex
Aluminum, tris(2-hydroxypropanoate-O1,O2)-
Aluminum, tris(2-hydroxypropanoato-O1,O2)-
aluminum tris(alpha-hydroxypropionate)
Aluminum, tris(2-(hydroxy-kappaO)propanoato-kappaO)-
Aluminum, tris[2-(hydroxy-.kappa.O)propanoato-.kappa.O]-
Aluminum lactate (Al(O3C3H5)3)
EINECS 242-670-9
Tris(2-hydroxypropanoato-O(sup 1),O(sup 2))aluminum
Aluminium-(RS)-lactat
Aluminium lacticum
UNII-V797H4GG0Z
aluminium trilactate
tris(2-hydroxypropanoato)aluminum
tris(lactato)aluminium
tris[2-(hydroxy-kappaO)propanoato-kappaO]aluminium
Chemical Function
Astringent
Deodorizer
pH regulating agent
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Aluminum Lactate allowed in the EU?
Aluminum Lactate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Aluminum Lactate do in cosmetics?
Aluminum Lactate functions as: Astringent, buffering agent, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 18917-91-4.
What is the NOAEL for Aluminum Lactate?
The NOAEL (No Observed Adverse Effect Level) for Aluminum Lactate is =10 mg/kg bw/day based on a reproduction toxicity study via oral: feed route in Mouse. A total of 2 study endpoints are available. Source: EFSA.
Is Aluminum Lactate used outside cosmetics?
Aluminum Lactate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Aluminum Lactate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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AMBERGRIS TINCTURE
GOOD
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