Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Ammonium Iodide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.01 mg/kg bw/day | oral | code:3544 | oral | REACH |
| NOAEL | 10 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 684 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >10 mg/kg bw/day | other | rat | oral | REACH |
Expert Verdict
Thyroid disruption risk with systemic absorption; iododerma/halogenoderma risk; not recommended for leave-on products without dedicated safety assessment; essentially pharmaceutical, not cosmetic
Frequently Asked Questions
Is Ammonium Iodide safe in cosmetics?
Thyroid disruption risk with systemic absorption; iododerma/halogenoderma risk; not recommended for leave-on products without dedicated safety assessment; essentially pharmaceutical, not cosmetic The EU classifies Ammonium Iodide as "prohibited". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Ammonium Iodide allowed in the EU?
Ammonium Iodide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Iodide do in cosmetics?
Ammonium Iodide functions as: No standard INCI cosmetic function assigned; historically pharmaceutical/topical. It is classified as a cosmetic ingredient in our database. CAS number: 12027-06-4.
What is the Margin of Safety for Ammonium Iodide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ammonium Iodide?
The NOAEL (No Observed Adverse Effect Level) for Ammonium Iodide is 0.01 mg/kg bw/day based on a oral study via oral route in code:3544. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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