Is Ammonium Thiocyanate safe in cosmetics?
Ammonium Thiocyanate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: restricted. 1 toxicological study endpoint(s) are available in our database.
Ammonium Thiocyanate
Also known as: Ammonium isothiocyanate, Ammonium rhodanate, Ammonium sulfocyanate, Thiocyanic acid, ammonium salt (1:1), Thiocyanic acid, ammonium salt (+13 more)
INCI: AMMONIUM THIOCYANATE
Ammonium Thiocyanate (CAS 1762-95-4) is a cosmetic cosmetic ingredient functioning as Reducing agent; used in hair-waving formulations. Reported NOAEL =20 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1762-95-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ammonium Thiocyanate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H318, H332, H412).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Reducing agent; used in hair-waving formulations
Safety Rating
MODERATE
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Not specifically restricted by FDA for cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ammonium Thiocyanate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Ammonium Thiocyanate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =20 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antiperspirant
Oxidizing agent
Reducing agent
Viscosity modifier
pH regulating agent
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Ammonium Thiocyanate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Ammonium Thiocyanate by CAS number or substance name.
Studies
1
Lowest NOAEL
20 mg/kg bw/day
Highest NOAEL
20 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Ammonium isothiocyanate
Ammonium rhodanate
Ammonium sulfocyanate
Thiocyanic acid, ammonium salt (1:1)
Thiocyanic acid, ammonium salt
Ammonium cyanide sulfide (NH4CNS)
Rhodanid
Ammonium sulfocyanide
EINECS 217-175-6
NSC 31184
Rhodanine, ammonium salt
Trans-aid
USAF EK-P-433
Weedazol tl
Ammoniumrhodanid
UNII-YYL9152Z1Y
217-175-6
EC No.: 217-175-6
Chemical Function
Viscosity modifier
pH regulating agent
Oxidizing agent
Reducing agent
Antiperspirant
Regulatory Lists
active_ingredient; Europe; Pesticides
inert_ingredient; non_food_use; Pesticides
CEDI
Indirect additives food contact (10/2018)
fracking; water
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3187560
Frequently Asked Questions
Is Ammonium Thiocyanate allowed in the EU?
Ammonium Thiocyanate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Thiocyanate do in cosmetics?
Ammonium Thiocyanate functions as: Reducing agent; used in hair-waving formulations. It is classified as a cosmetic ingredient in our database. CAS number: 1762-95-4.
What is the NOAEL for Ammonium Thiocyanate?
The NOAEL (No Observed Adverse Effect Level) for Ammonium Thiocyanate is =20 mg/kg bw/day based on a chronic study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Ammonium Thiocyanate used outside cosmetics?
Ammonium Thiocyanate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ammonium Thiocyanate have different safety status in cosmetics vs industrial chemicals?
Ammonium Thiocyanate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H318, H332, H412).
Compliance Tools
Check Ammonium Thiocyanate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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