Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Ammonium Thiolactate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 60 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 150 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 60 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Reducing agent for permanent waving with mandatory labeling warnings; milder odor than thioglycolate but pH-dependent stability requires alkaline conditions that increase irritation risk.
Frequently Asked Questions
Is Ammonium Thiolactate safe in cosmetics?
Reducing agent for permanent waving with mandatory labeling warnings; milder odor than thioglycolate but pH-dependent stability requires alkaline conditions that increase irritation risk. The EU classifies Ammonium Thiolactate as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Ammonium Thiolactate allowed in the EU?
Ammonium Thiolactate EU regulatory status: restricted. Maximum allowed concentration: 8%. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Thiolactate do in cosmetics?
Ammonium Thiolactate functions as: Reducing agent for permanent waving and hair straightening. It is classified as a cosmetic ingredient in our database. CAS number: 13419-67-5.
What is the Margin of Safety for Ammonium Thiolactate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ammonium Thiolactate?
The NOAEL (No Observed Adverse Effect Level) for Ammonium Thiolactate is 60 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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