Good Cosmetic Ingredient NOAEL Data

Amylfuran

INCI: AMYLFURAN

CAS Number
3777-69-3
Function
Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted by FDA; manufacturer responsibility under FD&C Act and MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Amylfuran. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 26 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 26 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Also known as 2-pentylfuran; naturally occurring furan derivative; furans as a class have been reviewed for genotoxicity, but amylfuran at fragrance-level concentrations is not flagged

โš ๏ธ
Concern Level: Low

Regulatory Flags

fragrance-component natural-origin ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Amylfuran safe in cosmetics?

Also known as 2-pentylfuran; naturally occurring furan derivative; furans as a class have been reviewed for genotoxicity, but amylfuran at fragrance-level concentrations is not flagged The EU classifies Amylfuran as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Amylfuran allowed in the EU?

Amylfuran EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amylfuran do in cosmetics?

Amylfuran functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 3777-69-3.

What is the Margin of Safety for Amylfuran?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Amylfuran?

The NOAEL (No Observed Adverse Effect Level) for Amylfuran is 26 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Amylfuran in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Amylfuran in your formulation.