Moderate Cosmetic Ingredient

Anacyclus Pyrethrum Root Extract

INCI: ANACYCLUS PYRETHRUM ROOT EXTRACT

CAS Number
84787-64-4
Function
Skin Conditioning; Antioxidant
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No CIR safety assessment on record. Commercially used in lotions, creams, toners, gels, and moisturisers. Acute oral LD50 >2000 mg/kg (Swiss mice) confirms low systemic toxicity at standard doses. At 2000 mg/kg oral dose, hepatic and renal stress observed. Dermal route at cosmetic concentrations considered low risk.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted in EU and US cosmetics with no current restrictions. Skin conditioning and antioxidant benefits are research-supported. Key concern is pellitorine transdermal absorption at higher use concentrations and Asteraceae family cross-reactivity for sensitive consumers; use at low concentrations in leave-on products warrants caution.

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Concern Level: Moderate

Regulatory Flags

no-cir-review asteraceae-family transdermal-absorption-concern pellitorine-active compositae-cross-reactivity-risk not-recommended-leave-on-high-concentration antioxidant-benefits traditional-medicine-use

Frequently Asked Questions

Is Anacyclus Pyrethrum Root Extract safe in cosmetics?

Permitted in EU and US cosmetics with no current restrictions. Skin conditioning and antioxidant benefits are research-supported. Key concern is pellitorine transdermal absorption at higher use concentrations and Asteraceae family cross-reactivity for sensitive consumers; use at low concentrations in leave-on products warrants caution. The EU classifies Anacyclus Pyrethrum Root Extract as "permitted". Safety rating: MODERATE.

Is Anacyclus Pyrethrum Root Extract allowed in the EU?

Anacyclus Pyrethrum Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Anacyclus Pyrethrum Root Extract do in cosmetics?

Anacyclus Pyrethrum Root Extract functions as: Skin Conditioning; Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84787-64-4.

What is the Margin of Safety for Anacyclus Pyrethrum Root Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Anacyclus Pyrethrum Root Extract compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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