Marsdenia Cundurango Bark Extract

INCI: MARSDENIA CUNDURANGO BARK EXTRACT

CAS Number
84787-66-6 (EC 284-108-5)
Function
Skin conditioning; improves skin barrier function, anti-aging, detoxification
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not on 21 CFR 700 prohibited/restricted list

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Condurangin glycosides are emetic/toxic at oral doses โ€” ensure product is for external use only; CITES status should be verified for sourcing; limited published dermal toxicity data; request supplier COA for condurangin content

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Marsdenia Cundurango Bark Extract safe in cosmetics?

Condurangin glycosides are emetic/toxic at oral doses โ€” ensure product is for external use only; CITES status should be verified for sourcing; limited published dermal toxicity data; request supplier COA for condurangin content The EU classifies Marsdenia Cundurango Bark Extract as "permitted". Safety rating: MODERATE.

Is Marsdenia Cundurango Bark Extract allowed in the EU?

Marsdenia Cundurango Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Marsdenia Cundurango Bark Extract do in cosmetics?

Marsdenia Cundurango Bark Extract functions as: Skin conditioning; improves skin barrier function, anti-aging, detoxification. It is classified as a cosmetic ingredient in our database. CAS number: 84787-66-6 (EC 284-108-5).

What is the Margin of Safety for Marsdenia Cundurango Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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