Andrographis Paniculata Leaf Extract

INCI: ANDROGRAPHIS PANICULATA LEAF EXTRACT

CAS Number
90244-84-1
Function
Astringent, skin conditioning, anti-inflammatory, skin lightening, anti-aging
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; FDA UNII: I49U6EUL9X

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Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potent bioactive with andrographolide's astringent properties; vasoconstriction activity noted, requiring caution around eyes at high concentrations to avoid irritation.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Andrographis Paniculata Leaf Extract safe in cosmetics?

Potent bioactive with andrographolide's astringent properties; vasoconstriction activity noted, requiring caution around eyes at high concentrations to avoid irritation. The EU classifies Andrographis Paniculata Leaf Extract as "permitted". Safety rating: GOOD.

Is Andrographis Paniculata Leaf Extract allowed in the EU?

Andrographis Paniculata Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Andrographis Paniculata Leaf Extract do in cosmetics?

Andrographis Paniculata Leaf Extract functions as: Astringent, skin conditioning, anti-inflammatory, skin lightening, anti-aging. It is classified as a cosmetic ingredient in our database. CAS number: 90244-84-1.

What is the Margin of Safety for Andrographis Paniculata Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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