Arginine Mandelate

INCI: ARGININE MANDELATE

CAS Number
Not widely published as a single CAS
Function
Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: Not individually reviewed; component-level safety supported (arginine and mandelic acid each independently reviewed)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

AHA photosensitivity concern โ€” EU and FDA guidance recommends sunscreen use with AHA-containing products; pH-dependent irritation; label must include sun protection warnings per 21 CFR 740.19 (US)

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Concern Level: Moderate

Frequently Asked Questions

Is Arginine Mandelate safe in cosmetics?

AHA photosensitivity concern โ€” EU and FDA guidance recommends sunscreen use with AHA-containing products; pH-dependent irritation; label must include sun protection warnings per 21 CFR 740.19 (US) The EU classifies Arginine Mandelate as "permitted". Safety rating: GOOD.

Is Arginine Mandelate allowed in the EU?

Arginine Mandelate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Arginine Mandelate do in cosmetics?

Arginine Mandelate functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not widely published as a single CAS.

What is the Margin of Safety for Arginine Mandelate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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