Ascorbyl Isostearate

INCI: ASCORBYL ISOSTEARATE

CAS Number
51222-59-4
Function
Skin-Conditioning Agent – Miscellaneous
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR-reviewed (2022): safe as used when formulated to be nonirritating/nonsensitizing; however, not reported as being used in any cosmetic products at the time of the review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Zero reported commercial uses as of 2022 CIR survey. If planning to use this ingredient, safety case would need to be established from scratch with read-across justification.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Ascorbyl Isostearate safe in cosmetics?

Zero reported commercial uses as of 2022 CIR survey. If planning to use this ingredient, safety case would need to be established from scratch with read-across justification. The EU classifies Ascorbyl Isostearate as "permitted". Safety rating: MODERATE.

Is Ascorbyl Isostearate allowed in the EU?

Ascorbyl Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ascorbyl Isostearate do in cosmetics?

Ascorbyl Isostearate functions as: Skin-Conditioning Agent – Miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: 51222-59-4.

What is the Margin of Safety for Ascorbyl Isostearate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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