Moderate Cosmetic Ingredient

Avocadamide DEA

INCI: AVOCADAMIDE DEA

CAS Number
124046-21-5
Function
Non-ionic surfactant; foam boosting; viscosity controlling
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. 0.5%
🇺🇸 US Status permitted
US Notes Allowed with caution - not prohibited, but the FDA has issued guidance on nitrosamine contamination in cosmetics containing DEA; industry is expected to ensure final products are free from nitrosamines

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Diethanolamine (DEA) derivatives can react with nitrosating agents to form potentially carcinogenic nitrosamines (NDELA); this is the primary regulatory and safety concern. Skin irritation possible at high concentrations.. Produced by reacting avocado oil fatty acids with diethanolamine; functions as a foam stabilizer and thickener; avocado-derived chain gives a richer fatty acid profile than standard coco-based DEA amides

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Concern Level: High

Frequently Asked Questions

Is Avocadamide DEA safe in cosmetics?

Diethanolamine (DEA) derivatives can react with nitrosating agents to form potentially carcinogenic nitrosamines (NDELA); this is the primary regulatory and safety concern. Skin irritation possible at high concentrations.. Produced by reacting avocado oil fatty acids with diethanolamine; functions as a foam stabilizer and thickener; avocado-derived chain gives a richer fatty acid profile than standard coco-based DEA amides The EU classifies Avocadamide DEA as "restricted". Safety rating: MODERATE.

Is Avocadamide DEA allowed in the EU?

Avocadamide DEA EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Avocadamide DEA do in cosmetics?

Avocadamide DEA functions as: Non-ionic surfactant; foam boosting; viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 124046-21-5.

What is the Margin of Safety for Avocadamide DEA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Avocadamide DEA compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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