Is Almond Oil PEG-6 Esters safe in cosmetics?
Almond Oil PEG-6 Esters has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.
Almond Oil PEG-6 Esters
INCI: ALMOND OIL PEG-6 ESTERS
Almond Oil PEG-6 Esters (CAS 124046-50-0) is a cosmetic emulsifier functioning as surfactant - emulsifying, skin conditioning - emollient, penetration enhancing. Reported NOAEL =3000 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 124046-50-0 →
Auto-generated CPSR Part A draft with source citations
Function
surfactant - emulsifying, skin conditioning - emollient, penetration enhancing
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR 2012 concluded all 130 PEGylated oils safe when formulated to be non-irritating; read-across from PEG-castor oils and structural analogs; no ingredient-specific VCRP data reported at time of review
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Almond Oil PEG-6 Esters.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Almond Oil PEG-6 Esters. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =3000 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =3000 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =3000 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =3000 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Fragrance
Softener and conditioner
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for Almond Oil PEG-6 Esters.
Regulatory Flags
penetration-enhancer
1,4-dioxane-impurity-risk
ethoxylated
read-across-safety
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Almond Oil PEG-6 Esters by CAS number or substance name.
Studies
4
Lowest NOAEL
3000 mg/kg/d
Highest NOAEL
3000 mg/kg/d
CIR_vision_codex
Chemical Function
Softener and conditioner
Emulsifier
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Almond Oil PEG-6 Esters allowed in the EU?
Almond Oil PEG-6 Esters EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Almond Oil PEG-6 Esters do in cosmetics?
Almond Oil PEG-6 Esters functions as: surfactant - emulsifying, skin conditioning - emollient, penetration enhancing. It is classified as a Emulsifier in our database. CAS number: 124046-50-0.
What is the NOAEL for Almond Oil PEG-6 Esters?
The NOAEL (No Observed Adverse Effect Level) for Almond Oil PEG-6 Esters is =3000 mg/kg/d based on a developmental toxicity study via oral route in rat. A total of 4 study endpoints are available. Source: CIR_vision_codex.
Compliance Tools
Check Almond Oil PEG-6 Esters compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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