Baicalein

INCI: BAICALEIN

CAS Number
491-67-8
Function
Antioxidant, skin conditioning (soothing, anti-inflammatory)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted; recognized flavonoid used in cosmetics. FDA UNII registered

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Do not confuse with Baicalin (CAS 21967-41-9), the glycoside form. Photostability should be verified in formulation.

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Concern Level: Low

Frequently Asked Questions

Is Baicalein safe in cosmetics?

Do not confuse with Baicalin (CAS 21967-41-9), the glycoside form. Photostability should be verified in formulation. The EU classifies Baicalein as "permitted". Safety rating: GOOD.

Is Baicalein allowed in the EU?

Baicalein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Baicalein do in cosmetics?

Baicalein functions as: Antioxidant, skin conditioning (soothing, anti-inflammatory). It is classified as a cosmetic ingredient in our database. CAS number: 491-67-8.

What is the Margin of Safety for Baicalein?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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