Moderate Antioxidant

Biochanin A

INCI: BIOCHANIN A

CAS Number
491-80-5
Function
Humectant, Skin Protecting, Skin Conditioning, Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restrictions. Falls under general cosmetic ingredient framework.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Biochanin A is a red clover-derived isoflavone that demethylates in vivo to genistein, which is subject to SCCS restrictions due to phytoestrogenic endocrine-disrupting activity; safety assessment must account for metabolite conversion despite lack of direct EU listing.

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Concern Level: High

Regulatory Flags

ENDOCRINE_DISRUPTOR

Frequently Asked Questions

Is Biochanin A safe in cosmetics?

Biochanin A is a red clover-derived isoflavone that demethylates in vivo to genistein, which is subject to SCCS restrictions due to phytoestrogenic endocrine-disrupting activity; safety assessment must account for metabolite conversion despite lack of direct EU listing. The EU classifies Biochanin A as "permitted". Safety rating: MODERATE.

Is Biochanin A allowed in the EU?

Biochanin A EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Biochanin A do in cosmetics?

Biochanin A functions as: Humectant, Skin Protecting, Skin Conditioning, Antioxidant. It is classified as a Antioxidant in our database. CAS number: 491-80-5.

What is the Margin of Safety for Biochanin A?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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