Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer

INCI: BIS-HEA POLY(1,4-BUTANEDIOL)-9/TDI COPOLYMER

CAS Number
Not assigned (polymeric)
Function
Nail conditioning, binding
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA: no specific ban on the polymer; CIR: covered under Polyurethanes โ€” safe only if residual TDI is non-detectable

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

TDI-based copolymer requiring batch-level residual isocyanate testing; TDI is IARC Group 2B possible carcinogen and OSHA-regulated respiratory sensitizer with CIR safety conditional on non-detectable residual TDI.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer safe in cosmetics?

TDI-based copolymer requiring batch-level residual isocyanate testing; TDI is IARC Group 2B possible carcinogen and OSHA-regulated respiratory sensitizer with CIR safety conditional on non-detectable residual TDI. The EU classifies Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer as "restricted". Safety rating: MODERATE.

Is Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer allowed in the EU?

Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer do in cosmetics?

Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer functions as: Nail conditioning, binding. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (polymeric).

What is the Margin of Safety for Bis-HEA Poly(1,4-Butanediol)-9/TDI Copolymer?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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