Bis-HEA Polycaprolactone/SMDI Copolymer

INCI: BIS-HEA POLYCAPROLACTONE/SMDI COPOLYMER

CAS Number
52404-33-8
Function
Film forming; nail conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Residual unreacted monomers are the key concern: HEA (2-hydroxyethyl acrylate) is a known skin sensitizer, and SMDI (4,4โ€ฒ-methylenebis(cyclohexyl isocyanate)) is a respiratory/skin sensitizer if present in unreacted form. The finished copolymer itself is considered inert. Manufacturers must control residual monomer levels rigorously.. Polyurethane acrylate copolymer synthesized from 2-hydroxyethyl acrylate, caprolactone, and SMDI; provides a hard, durable, glossy film on nails; UV-curable whe...

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Bis-HEA Polycaprolactone/SMDI Copolymer safe in cosmetics?

Residual unreacted monomers are the key concern: HEA (2-hydroxyethyl acrylate) is a known skin sensitizer, and SMDI (4,4โ€ฒ-methylenebis(cyclohexyl isocyanate)) is a respiratory/skin sensitizer if present in unreacted form. The finished copolymer itself is considered inert. Manufacturers must control residual monomer levels rigorously.. Polyurethane acrylate copolymer synthesized from 2-hydroxyethyl acrylate, caprolactone, and SMDI; provides a hard, durable, glossy film on nails; UV-curable whe... The EU classifies Bis-HEA Polycaprolactone/SMDI Copolymer as "permitted". Safety rating: MODERATE.

Is Bis-HEA Polycaprolactone/SMDI Copolymer allowed in the EU?

Bis-HEA Polycaprolactone/SMDI Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis-HEA Polycaprolactone/SMDI Copolymer do in cosmetics?

Bis-HEA Polycaprolactone/SMDI Copolymer functions as: Film forming; nail conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 52404-33-8.

What is the Margin of Safety for Bis-HEA Polycaprolactone/SMDI Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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