Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer

INCI: BIS-HEA/HEMA POLY(1,4-BUTANEDIOL)-41/1,2-BUTANEDIOL/IPDI COPOLYMER

CAS Number
Not publicly listed in available databases
Function
Nail conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual acrylate/methacrylate sensitization risk - this ingredient contains both HEA and HEMA (2-hydroxyethyl methacrylate) end-caps. HEMA is a well-documented contact allergen and is increasingly scrutinized in the EU nail industry (proposals to restrict HEMA in consumer nail products have been discussed). IPDI residual monomer risk also applies. This ingredient requires the most careful residual monomer control of the group.. Long polytetramethylene glycol chain (repeat unit 41) provides excep...

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer safe in cosmetics?

Dual acrylate/methacrylate sensitization risk - this ingredient contains both HEA and HEMA (2-hydroxyethyl methacrylate) end-caps. HEMA is a well-documented contact allergen and is increasingly scrutinized in the EU nail industry (proposals to restrict HEMA in consumer nail products have been discussed). IPDI residual monomer risk also applies. This ingredient requires the most careful residual monomer control of the group.. Long polytetramethylene glycol chain (repeat unit 41) provides excep... The EU classifies Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer as "permitted". Safety rating: MODERATE.

Is Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer allowed in the EU?

Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer do in cosmetics?

Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer functions as: Nail conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in available databases.

What is the Margin of Safety for Bis-HEA/HEMA Poly(1,4-Butanediol)-41/1,2-Butanediol/IPDI Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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