Bis-Retinamido Methylpentane

INCI: BIS-RETINAMIDO METHYLPENTANE

CAS Number
1354766-25-8
Function
Skin conditioning (anti-aging retinoid derivative, RS-2A)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.05%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not separately CIR-reviewed. FDA does not restrict retinoid derivatives beyond general safety requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU Annex III restricted use with 0.05% maximum concentration. Light-unstable formulation requiring opaque, airtight packaging protected from light and heat. Labeling must declare vitamin A content and advise consumers to consider cumulative daily retinoid intake.

โš ๏ธ
Concern Level: Moderate

Frequently Asked Questions

Is Bis-Retinamido Methylpentane safe in cosmetics?

EU Annex III restricted use with 0.05% maximum concentration. Light-unstable formulation requiring opaque, airtight packaging protected from light and heat. Labeling must declare vitamin A content and advise consumers to consider cumulative daily retinoid intake. The EU classifies Bis-Retinamido Methylpentane as "restricted". Safety rating: GOOD.

Is Bis-Retinamido Methylpentane allowed in the EU?

Bis-Retinamido Methylpentane EU regulatory status: restricted. Maximum allowed concentration: 0.05%. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis-Retinamido Methylpentane do in cosmetics?

Bis-Retinamido Methylpentane functions as: Skin conditioning (anti-aging retinoid derivative, RS-2A). It is classified as a cosmetic ingredient in our database. CAS number: 1354766-25-8.

What is the Margin of Safety for Bis-Retinamido Methylpentane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Bis-Retinamido Methylpentane in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Bis-Retinamido Methylpentane in your formulation.