Boehmeria Nivea Leaf Extract

INCI: BOEHMERIA NIVEA LEAF EXTRACT

CAS Number
2246379-81-5 (FEMA)
Function
Skin conditioning; FEMA GRAS #4956 for flavor use
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FEMA GRAS #4956 โ€” Generally Recognized As Safe for flavor use. No standalone CIR monograph for cosmetic use.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Protein content (8โ€“15%) raises theoretical concern for protein contact dermatitis in sensitive individuals; FEMA GRAS designation covers oral route only, and dermal safety extrapolation is supportive but not definitive.

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Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Boehmeria Nivea Leaf Extract safe in cosmetics?

Protein content (8โ€“15%) raises theoretical concern for protein contact dermatitis in sensitive individuals; FEMA GRAS designation covers oral route only, and dermal safety extrapolation is supportive but not definitive. The EU classifies Boehmeria Nivea Leaf Extract as "permitted". Safety rating: GOOD.

Is Boehmeria Nivea Leaf Extract allowed in the EU?

Boehmeria Nivea Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Boehmeria Nivea Leaf Extract do in cosmetics?

Boehmeria Nivea Leaf Extract functions as: Skin conditioning; FEMA GRAS #4956 for flavor use. It is classified as a cosmetic ingredient in our database. CAS number: 2246379-81-5 (FEMA).

What is the Margin of Safety for Boehmeria Nivea Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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