Bromothymol Blue

INCI: BROMOTHYMOL BLUE

CAS Number
76-59-5 (free acid); 34722-90-2 (sodium salt)
Function
Hair colorant (non-oxidative hair dye)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not calculable โ€” SCCS noted SED exceeds TTC threshold for Cramer Class III; no repeat-dose NOAEL available

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

SCCS explicitly stated safety cannot be confirmed due to SED exceeding Cramer III TTC threshold and lack of repeat-dose NOAEL data. Purity varies significantly between suppliers (90โ€“97%) with impurities including thymol blue and mono-brominated isomers.

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Concern Level: Moderate

Regulatory Flags

colorant eu_cosing_listed

Frequently Asked Questions

Is Bromothymol Blue safe in cosmetics?

SCCS explicitly stated safety cannot be confirmed due to SED exceeding Cramer III TTC threshold and lack of repeat-dose NOAEL data. Purity varies significantly between suppliers (90โ€“97%) with impurities including thymol blue and mono-brominated isomers. The EU classifies Bromothymol Blue as "permitted". Safety rating: MODERATE.

Is Bromothymol Blue allowed in the EU?

Bromothymol Blue EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bromothymol Blue do in cosmetics?

Bromothymol Blue functions as: Hair colorant (non-oxidative hair dye). It is classified as a cosmetic ingredient in our database. CAS number: 76-59-5 (free acid); 34722-90-2 (sodium salt).

What is the Margin of Safety for Bromothymol Blue?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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