Brucine Sulfate

INCI: BRUCINE SULFATE

CAS Number
4845-99-2 (heptahydrate)
Function
Denaturant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No published MoS โ€” critical gap given known toxicity profile

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

RED FLAG: No established margin of safety despite moderate safety profile and known toxicity concerns.

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Concern Level: Moderate

Frequently Asked Questions

Is Brucine Sulfate safe in cosmetics?

RED FLAG: No established margin of safety despite moderate safety profile and known toxicity concerns. The EU classifies Brucine Sulfate as "permitted". Safety rating: MODERATE.

Is Brucine Sulfate allowed in the EU?

Brucine Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Brucine Sulfate do in cosmetics?

Brucine Sulfate functions as: Denaturant. It is classified as a cosmetic ingredient in our database. CAS number: 4845-99-2 (heptahydrate).

What is the Margin of Safety for Brucine Sulfate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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