Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for C12-14 Pareth-7. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=150 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=150 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
1,4-Dioxane/ethylene oxide impurities; penetration enhancement.
Regulatory Flags
Frequently Asked Questions
Is C12-14 Pareth-7 safe in cosmetics?
1,4-Dioxane/ethylene oxide impurities; penetration enhancement. The EU classifies C12-14 Pareth-7 as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is C12-14 Pareth-7 allowed in the EU?
C12-14 Pareth-7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does C12-14 Pareth-7 do in cosmetics?
C12-14 Pareth-7 functions as: Surfactant – Emulsifying; Surfactant – Cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 68439-50-9.
What is the Margin of Safety for C12-14 Pareth-7?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for C12-14 Pareth-7?
The NOAEL (No Observed Adverse Effect Level) for C12-14 Pareth-7 is >=500 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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