Is Calcium Fluoride safe in cosmetics?
Calcium Fluoride has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Calcium Fluoride
Also known as: Acid-spar, EINECS 232-188-7, Fluorspar, Liparite, Met-spar (+8 more)
INCI: CALCIUM FLUORIDE
Calcium Fluoride (CAS 7789-75-5) is a cosmetic cosmetic ingredient functioning as Oral care agent (anticaries). EU Regulation 1223/2009 status: restricted, max 0.15%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 7789-75-5 →
Auto-generated CPSR Part A draft with source citations
Function
Oral care agent (anticaries)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
calcium difluoride
InChIKey
WUKWITHWXAAZEY-UHFFFAOYSA-L
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.15%
US US Status
permitted
US Notes
FDA OTC Monograph anticaries agent; regulated under 21 CFR 355
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Fluoride.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: Oral products. Max: 0.15% calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15%.
BRIN Brazil/India Cosmetics
India: Restricted · max 0.15% calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15%
Additional Ingredient Properties
1 property record from structured ingredient metadata.
mineral_clay
{"cas_number": "7789-75-5", "ingredient_class": "calcium_compound", "chemical_formula": "CaF2", "mineral_origin": "natural", "particle_size_range_um": "0.5-10", "surface_area_m2_per_g": "1-10", "crystal_structure": "cubic", "color_appearance": "white/transparent", "opacity": "transparent", "refractive_index": "1.43", "oil_absorption_g_per_100g": "5-15", "water_absorption_capacity": "low", "surface…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Evidence for Carcinogenicity
A4; Not classifiable as a human carcinogen. /Fluorides, as F/
Source: Hazardous Substances Data Bank (HSDB)
ICSC Safety Card
1323
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Pharmaceutical
Regulatory List Membership (1)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Calcium Fluoride.
Regulatory Flags
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Calcium Fluoride by CAS number or substance name.
Studies
126
Lowest NOAEL
0.59 mg/kg bw/day
Highest NOAEL
800 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Acid-spar
EINECS 232-188-7
Fluorspar
Liparite
Met-spar
Natural fluorite
Calcium fluoratum
UNII-O3B55K4YKI
Calcarea fluorica
CaF2
Kalziumdifluorid
Kalziumfluorid
fluorite
Chemical Function
Pharmaceutical
Regulatory Lists
drinking_water; Europe; manufacturing; plastic_additive
Europe; supplements
Europe; Personal care; restricted
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Calcium Fluoride allowed in the EU?
Calcium Fluoride EU regulatory status: restricted. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Fluoride do in cosmetics?
Calcium Fluoride functions as: Oral care agent (anticaries). It is classified as a cosmetic ingredient in our database. CAS number: 7789-75-5.
Is Calcium Fluoride used outside cosmetics?
Calcium Fluoride also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Calcium Fluoride compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Good
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