Calcium Monofluorophosphate

INCI: CALCIUM MONOFLUOROPHOSPHATE

CAS Number
7789-74-4
Function
Antiplaque agent (oral care)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.15%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Adequate at permitted concentrations โ€” well-established fluoride toxicology; acute toxicity concern only at gross over-ingestion

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Fluoride toxicity risk if swallowed in large amounts, especially in children; restricted to oral care products only with mandatory labeling in EU.

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Concern Level: Moderate

Regulatory Flags

eu_cosing_listed

Frequently Asked Questions

Is Calcium Monofluorophosphate safe in cosmetics?

Fluoride toxicity risk if swallowed in large amounts, especially in children; restricted to oral care products only with mandatory labeling in EU. The EU classifies Calcium Monofluorophosphate as "restricted". Safety rating: MODERATE.

Is Calcium Monofluorophosphate allowed in the EU?

Calcium Monofluorophosphate EU regulatory status: restricted. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Monofluorophosphate do in cosmetics?

Calcium Monofluorophosphate functions as: Antiplaque agent (oral care). It is classified as a cosmetic ingredient in our database. CAS number: 7789-74-4.

What is the Margin of Safety for Calcium Monofluorophosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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