Good Cosmetic Ingredient

Calcium Glycerophosphate

INCI: CALCIUM GLYCEROPHOSPHATE

CAS Number
27214-00-2 (primary); also 126-95-4 / 1336-00-1 / 58409-70-4 (isomeric variants)
Function
Antiplaque; Oral care
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically CIR-reviewed; classified as GRAS food additive; pharmaceutical use as calcium/phosphorus supplement

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Primarily formulated for oral care products; if used in skin-care, verify intended application is supported by product-type safety data

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Concern Level: Low

Regulatory Flags

eu_children_restricted fda_food_additive

Frequently Asked Questions

Is Calcium Glycerophosphate safe in cosmetics?

Primarily formulated for oral care products; if used in skin-care, verify intended application is supported by product-type safety data The EU classifies Calcium Glycerophosphate as "permitted". Safety rating: GOOD.

Is Calcium Glycerophosphate allowed in the EU?

Calcium Glycerophosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Glycerophosphate do in cosmetics?

Calcium Glycerophosphate functions as: Antiplaque; Oral care. It is classified as a cosmetic ingredient in our database. CAS number: 27214-00-2 (primary); also 126-95-4 / 1336-00-1 / 58409-70-4 (isomeric variants).

What is the Margin of Safety for Calcium Glycerophosphate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Calcium Glycerophosphate compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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