Moderate Cosmetic Ingredient NOAEL Data

Caprylyl Glucoside

INCI: CAPRYLYL GLUCOSIDE

CAS Number
68515-73-1
Function
Nonionic surfactant, emulsifier, solubilizer, cleansing agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Listed as UNII ingredient; safe for food and cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Caprylyl Glucoside. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOEL 500 mg/kg bw/day oral rat oral REACH
LOEL 500 mg/kg bw/day oral rat oral REACH

Expert Verdict

Nonionic surfactant that may cause mild skin irritation and severe eye irritation at high concentrations; non-irritating when properly formulated.

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Concern Level: Moderate

Regulatory Flags

epa_safer_alternative

Frequently Asked Questions

Is Caprylyl Glucoside safe in cosmetics?

Nonionic surfactant that may cause mild skin irritation and severe eye irritation at high concentrations; non-irritating when properly formulated. The EU classifies Caprylyl Glucoside as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Caprylyl Glucoside allowed in the EU?

Caprylyl Glucoside EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Caprylyl Glucoside do in cosmetics?

Caprylyl Glucoside functions as: Nonionic surfactant, emulsifier, solubilizer, cleansing agent. It is classified as a cosmetic ingredient in our database. CAS number: 68515-73-1.

What is the Margin of Safety for Caprylyl Glucoside?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Caprylyl Glucoside?

The NOAEL (No Observed Adverse Effect Level) for Caprylyl Glucoside is 500 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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