Chamomile Extract

INCI: MATRICARIA CHAMOMILLA FLOWER EXTRACT

CAS Number
84082-60-0
Function
Anti-inflammatory; bisabolol, chamazulene
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA. GRAS under 21 CFR Parts 182 and 184 for food/flavor use. FDA determined data inadequate to support OTC drug use. CIR 2018 Amended Safety Assessment concluded safe when formulated to be nonsensitizing. Industry practice up to 0.5% extract in leave-on products.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU: Permitted as skin conditioning and fragrance ingredient; not listed in Annex II or III of EC 1223/2009. US: GRAS under 21 CFR 182/184 for food use; CIR 2018 concluded safe when formulated to be nonsensitizing. Key concern: cross-reactivity risk in Asteraceae-allergic individuals.

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Concern Level: Low

Regulatory Flags

asteraceae-cross-reactivity sensitization-in-allergy-prone botanical-complex-mixture no-formal-dermal-absorption-data gras-food-grade eu_children_restricted

Frequently Asked Questions

Is Chamomile Extract safe in cosmetics?

EU: Permitted as skin conditioning and fragrance ingredient; not listed in Annex II or III of EC 1223/2009. US: GRAS under 21 CFR 182/184 for food use; CIR 2018 concluded safe when formulated to be nonsensitizing. Key concern: cross-reactivity risk in Asteraceae-allergic individuals. The EU classifies Chamomile Extract as "permitted". Safety rating: GOOD.

Is Chamomile Extract allowed in the EU?

Chamomile Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Chamomile Extract do in cosmetics?

Chamomile Extract functions as: Anti-inflammatory; bisabolol, chamazulene. It is classified as a Active Ingredient in our database. CAS number: 84082-60-0.

What is the Margin of Safety for Chamomile Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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