Good Active Ingredient Dermal Penetration

VP/VA Copolymer

INCI: VP/VA COPOLYMER

CAS Number
25086-89-9
Function
Film-forming polymer; hair fixative; binder
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
EU Max Conc. 44%
🇺🇸 US Status permitted
US Notes CIR safe as used (reaffirmed 2003); residual vinyl acetate monomer spec compliance is a manufacturing requirement; IARC Group 2B impurity (vinyl acetate) — tight specs essential

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Dermal Penetration Profile

Skin absorption and penetration characteristics of VP/VA Copolymer, relevant to systemic exposure and MoS calculations.

Absorption %
0%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
Variable Da
Log P
n/a
Systemic Absorption
no
Topical Bioavailability
0%
Safety Margin Factor
none

Source: CIR

Expert Verdict

Safe when manufactured to tight residual monomer specifications (vinyl acetate <100 ppm preferred, ≤1,000 ppm maximum; vinylpyrrolidone ≤1,000 ppm). Avoid high concentrations in eye-area products due to alcohol-mediated irritation potential.

⚠️
Concern Level: Low

Regulatory Flags

residual-monomer-concern iarc-2b-impurity eye-irritation-risk spray-caution eu_children_restricted

Frequently Asked Questions

Is VP/VA Copolymer safe in cosmetics?

Safe when manufactured to tight residual monomer specifications (vinyl acetate <100 ppm preferred, ≤1,000 ppm maximum; vinylpyrrolidone ≤1,000 ppm). Avoid high concentrations in eye-area products due to alcohol-mediated irritation potential. The EU classifies VP/VA Copolymer as "permitted". Safety rating: GOOD.

Is VP/VA Copolymer allowed in the EU?

VP/VA Copolymer EU regulatory status: permitted. Maximum allowed concentration: 44%. This is based on EU Regulation 1223/2009 and its amendments.

What does VP/VA Copolymer do in cosmetics?

VP/VA Copolymer functions as: Film-forming polymer; hair fixative; binder. It is classified as a Active Ingredient in our database. CAS number: 25086-89-9.

What is the Margin of Safety for VP/VA Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check VP/VA Copolymer compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Colloidal Oatmeal
Excellent
Hydroxypropyl Chitosan
Excellent
Elastic Vesicles
Good
Menthol
Good
Sulfur
Good
Browse all 30,000+ ingredients →
📱

Is VP/VA Copolymer in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for VP/VA Copolymer in your formulation.

Ingredient Decoder MoS Calculator