Chymotrypsin

INCI: CHYMOTRYPSIN

CAS Number
9004-07-3
Function
Enzyme
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for use in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Chymotrypsin is a proteolytic enzyme with restricted use in the EU and permitted status in the US, though its margin of safety is not established.

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Concern Level: Moderate

Frequently Asked Questions

Is Chymotrypsin safe in cosmetics?

Chymotrypsin is a proteolytic enzyme with restricted use in the EU and permitted status in the US, though its margin of safety is not established. The EU classifies Chymotrypsin as "restricted". Safety rating: MODERATE.

Is Chymotrypsin allowed in the EU?

Chymotrypsin EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Chymotrypsin do in cosmetics?

Chymotrypsin functions as: Enzyme. It is classified as a cosmetic ingredient in our database. CAS number: 9004-07-3.

What is the Margin of Safety for Chymotrypsin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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