NOAEL Studies Colorant

CI 15850 Red 7 Lake NOAEL Studies

INCI: CI 15850

CAS: 5858-81-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
NTP ICE acute oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE acute oral LD50 >10800 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_8024; row=11121; data_type=In Vivo; mixture=Chemical; chemical_name=FD&C Red No. 6; preferred_name=C.I. Pigment Red 57; dtxsid=DTXSID6064038; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6064038; source_file=acute_oral.xlsx
SCCNFP Opinion 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCNFP Opinion NOAEL =150 mg/kg bw/day rat oral chronic NOAEL study p.8
SCCNFP Opinion NOAEL =150 mg/kg rat oral 18 months reproductive toxicity p.16
SCCS Opinion 5 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =0 mg/kg bw/day dog oral Chronic NOAEL study Ref.: Add ref A, B 3, p.16
SCCS Opinion NOAEL =0.003 mg/kg bw/d rat - - NOAEL study p.25
SCCS Opinion NOAEL =100 mg/kg bw/day dog - Chronic NOAEL study Ref.: Add ref A, B 3, p.16
SCCS Opinion NOAEL =100 mg/kg bw/d rat oral chronic genotoxicity p.26
SCCS Opinion NOAEL =150 mg/kg bw/day rat - chronic NOAEL study p.16
Regulatory source 8 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 150 mg/kg bw/day rat oral chronic - p.8
Regulatory source reproductive toxicity 150 mg/kg rat oral 18 months reproductive toxicity p.16
Regulatory source - 0 mg/kg bw/day dog oral Chronic - p.16
Regulatory source - 0.003 mg/kg bw/d rat - - - p.25
Regulatory source - 100 mg/kg bw/day dog - Chronic - p.16
Regulatory source - 100 mg/kg bw/day dog oral Chronic - p.16
Regulatory source - 150 mg/kg bw/day rat - chronic - p.16
Regulatory source genotoxicity 100 mg/kg bw/d rat oral chronic genotoxicity p.26
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 481744AI4O UNII - - - chemical -