Good Cosmetic Ingredient NOAEL Data

CI 69800

INCI: VAT BLUE 6

CAS Number
130-20-1
Function
Colorant (blue vat dye — anthraquinone class)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status prohibited
US Notes Not listed as a separately permitted color additive for cosmetics in FDA tables

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for CI 69800. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=1000 mg/kg bw/day oral rat oral REACH
NOAEL >=1000 mg/kg bw/day oral - oral REACH

Expert Verdict

Permitted in EU cosmetics but prohibited in US-market cosmetics as it is not an FDA-approved color additive.

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Concern Level: Low

Regulatory Flags

colorant eu_cosing_listed

Frequently Asked Questions

Is CI 69800 safe in cosmetics?

Permitted in EU cosmetics but prohibited in US-market cosmetics as it is not an FDA-approved color additive. The EU classifies CI 69800 as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is CI 69800 allowed in the EU?

CI 69800 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 69800 do in cosmetics?

CI 69800 functions as: Colorant (blue vat dye — anthraquinone class). It is classified as a cosmetic ingredient in our database. CAS number: 130-20-1.

What is the Margin of Safety for CI 69800?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for CI 69800?

The NOAEL (No Observed Adverse Effect Level) for CI 69800 is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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