Good Cosmetic Ingredient

CI 75100

CAS Number
8022-19-3
Function
Colorant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA-regulated as Saffron (21 CFR 73.500) for food use, exempt from certification; saffron listed under 21 CFR Part 73 Subpart C for cosmetic use; saffron oleoresin was delisted (1966) — only saffron (stigma extract) permitted; GMP compliance required; EU Annex IV-permitted natural carotenoid colorant

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Natural saffron colorant from Crocus sativus with long history of safe human use; EU Annex IV-permitted and FDA exempt from certification; plant-derived carotenoid suitable across wide range of cosmetic products.

⚠️
Concern Level: Low

Regulatory Flags

natural-origin fda-exempt-certification carotenoid plant-derived antioxidant eu-annex-iv ifra_fragrance

Frequently Asked Questions

Is CI 75100 safe in cosmetics?

Natural saffron colorant from Crocus sativus with long history of safe human use; EU Annex IV-permitted and FDA exempt from certification; plant-derived carotenoid suitable across wide range of cosmetic products. The EU classifies CI 75100 as "permitted". Safety rating: GOOD.

Is CI 75100 allowed in the EU?

CI 75100 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 75100 do in cosmetics?

CI 75100 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 8022-19-3.

What is the Margin of Safety for CI 75100?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check CI 75100 compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

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