Good Cosmetic Ingredient NOAEL Data

Cinnamyl Propionate

INCI: CINNAMYL PROPIONATE

CAS Number
7492-66-2
Function
Fragrance ingredient (fruity/balsamic note)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA listed as food flavoring substance; no CIR safety assessment published; not restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Cinnamyl Propionate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 56 mg/kg bw/day oral rat oral REACH
NOAEL 125 other oral rat oral REACH

Expert Verdict

Cinnamyl alcohol metabolite is an EU Annex III fragrance allergen requiring labeling above 0.001% (leave-on) / 0.01% (rinse-off); confirm IFRA compliance

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Cinnamyl Propionate safe in cosmetics?

Cinnamyl alcohol metabolite is an EU Annex III fragrance allergen requiring labeling above 0.001% (leave-on) / 0.01% (rinse-off); confirm IFRA compliance The EU classifies Cinnamyl Propionate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Cinnamyl Propionate allowed in the EU?

Cinnamyl Propionate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cinnamyl Propionate do in cosmetics?

Cinnamyl Propionate functions as: Fragrance ingredient (fruity/balsamic note). It is classified as a cosmetic ingredient in our database. CAS number: 7492-66-2.

What is the Margin of Safety for Cinnamyl Propionate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cinnamyl Propionate?

The NOAEL (No Observed Adverse Effect Level) for Cinnamyl Propionate is 56 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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