cis-3-Hexenyl Isovalerate

INCI: CIS-3-HEXENYL ISOVALERATE

CAS Number
35154-45-1
Function
Fragrance ingredient with sweet, green, apple-like, and buttery notes
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FEMA GRAS; RIFM safety assessed and cleared; Cramer Class I

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

IFRA max use levels: 0.023% axillae, 0.46% face/body, 0.077% lip; negative phototoxicity in rabbit study at 25%

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is cis-3-Hexenyl Isovalerate safe in cosmetics?

IFRA max use levels: 0.023% axillae, 0.46% face/body, 0.077% lip; negative phototoxicity in rabbit study at 25% The EU classifies cis-3-Hexenyl Isovalerate as "permitted". Safety rating: EXCELLENT.

Is cis-3-Hexenyl Isovalerate allowed in the EU?

cis-3-Hexenyl Isovalerate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does cis-3-Hexenyl Isovalerate do in cosmetics?

cis-3-Hexenyl Isovalerate functions as: Fragrance ingredient with sweet, green, apple-like, and buttery notes. It is classified as a cosmetic ingredient in our database. CAS number: 35154-45-1.

What is the Margin of Safety for cis-3-Hexenyl Isovalerate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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