Regulatory Status
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Safety Data
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Expert Verdict
RIFM safety assessment found mixed ionones are not genotoxic, with adequate margins of exposure for repeated dose toxicity, reproductive toxicity, and local respiratory toxicity. Not expected to be phototoxic. Not classified as PBT (Persistent, Bioaccumulative, Toxic). Characterized by a warm, woody-violet, orris-like aroma. Synonyms include cyclocitrylidenacetone and irisone. Consists of α, β, and γ isomers naturally found in many essential oils
Regulatory Flags
Frequently Asked Questions
Is Mixed Ionones safe in cosmetics?
RIFM safety assessment found mixed ionones are not genotoxic, with adequate margins of exposure for repeated dose toxicity, reproductive toxicity, and local respiratory toxicity. Not expected to be phototoxic. Not classified as PBT (Persistent, Bioaccumulative, Toxic). Characterized by a warm, woody-violet, orris-like aroma. Synonyms include cyclocitrylidenacetone and irisone. Consists of α, β, and γ isomers naturally found in many essential oils The EU classifies Mixed Ionones as "permitted". Safety rating: MODERATE.
Is Mixed Ionones allowed in the EU?
Mixed Ionones EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Mixed Ionones do in cosmetics?
Mixed Ionones functions as: Fragrance ingredient; declared under "PARFUM" on cosmetic labels. It is classified as a cosmetic ingredient in our database. CAS number: 8013-90-9 (mixture); individual isomers include 14901-07-6 (β-ionone), 127-41-3 (α-ionone), 79-76-5 (γ-ionone).
What is the Margin of Safety for Mixed Ionones?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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