Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Citral Diethyl Acetal. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 56 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 125 other | oral | rat | oral | REACH |
Expert Verdict
Acid-catalyzed hydrolysis can release free citral (EU allergen); pH-dependent stability must be formulated above pH 4.5 to minimize hydrolysis
Regulatory Flags
Frequently Asked Questions
Is Citral Diethyl Acetal safe in cosmetics?
Acid-catalyzed hydrolysis can release free citral (EU allergen); pH-dependent stability must be formulated above pH 4.5 to minimize hydrolysis The EU classifies Citral Diethyl Acetal as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Citral Diethyl Acetal allowed in the EU?
Citral Diethyl Acetal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Citral Diethyl Acetal do in cosmetics?
Citral Diethyl Acetal functions as: Fragrance ingredient (citrus-green note). It is classified as a cosmetic ingredient in our database. CAS number: 7492-66-2.
What is the Margin of Safety for Citral Diethyl Acetal?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Citral Diethyl Acetal?
The NOAEL (No Observed Adverse Effect Level) for Citral Diethyl Acetal is 56 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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