Is Citronellyloxy Acetaldehyde safe in cosmetics?
Citronellyloxy Acetaldehyde has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Citronellyloxy Acetaldehyde
Also known as: 2-01-00-00864, BRN 1767678, Citronellyloxyacetaldehyde, 6,10-Dimethyl-3-oxa-9-undecenal, EINECS 231-324-2 (+5 more)
INCI: CITRONELLYLOXY ACETALDEHYDE
Citronellyloxy Acetaldehyde (CAS 7492-67-3) is a cosmetic cosmetic ingredient functioning as Fragrance / Perfuming agent with Muguet/lily-of-the-valley note. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 7492-67-3 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance / Perfuming agent with Muguet/lily-of-the-valley note
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-(3,7-dimethyloct-6-enoxy)acetaldehyde
InChIKey
LMETVDMCIJNNKH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FEMA GRAS (No. 2310); FDA-listed as substance added to food. Not separately reviewed by CIR.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Citronellyloxy Acetaldehyde.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | 100 | 0 | 3550 | 3550 | non-sensitizer |
| HMT | - | 0 | 5184 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
592
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
CITRONELLYLOXYACETALDEHYDE | 2023 | Not evaluated | JECFA requests that updated exposure data (including both MSDI and SPET values) be provided for the flavouring agents citronelloxyacetaldehyde (No. 592), 1,3-nonanediol acetate (No. 605), levulinic acid (No. 606), hydroxycitronellal diethyl acetal (No. 613), diethyl malonate (No. 614), diethyl tartrate (No. 622) and triethyl citrate (No. 629) wit
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Citronellyloxy Acetaldehyde.
Regulatory Flags
fragrance-component
epa_safer_alternative
ifra_fragrance
fda_food_additive
Known Synonyms
2-01-00-00864
BRN 1767678
Citronellyloxyacetaldehyde
6,10-Dimethyl-3-oxa-9-undecenal
EINECS 231-324-2
FEMA No. 2310
Muget aldehyde
NSC 46126
UNII-6PS292RE8D
Citronelloxyacetaldehyde
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
SCIL (9/2019)
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3729330
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CITRONELLOXYACETALDEHYDE
Food Category
flavoring
Frequently Asked Questions
Is Citronellyloxy Acetaldehyde allowed in the EU?
Citronellyloxy Acetaldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Citronellyloxy Acetaldehyde do in cosmetics?
Citronellyloxy Acetaldehyde functions as: Fragrance / Perfuming agent with Muguet/lily-of-the-valley note. It is classified as a cosmetic ingredient in our database. CAS number: 7492-67-3.
Is Citronellyloxy Acetaldehyde used outside cosmetics?
Citronellyloxy Acetaldehyde also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Citronellyloxy Acetaldehyde compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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