Citrus Grandis Leaf Extract

INCI: CITRUS GRANDIS (GRAPEFRUIT) LEAF EXTRACT

CAS Number
90045-43-5 / 8016-20-4
Function
Astringent; fragrance; skin conditioning; tonic
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.506%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA: Citrus leaf essential oils GRAS (21 CFR 182.20). Not specifically restricted.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU Annex III restricted due to furocoumarin content. Verify furocoumarin levels and pesticide residue status for leaf-derived botanicals. Fragrance allergen labeling required if limonene/linalool/citral exceed declaration thresholds (0.001% rinse-off; 0.01% leave-on per EU Reg. 1223/2009 Annex III).

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen fragrance-component natural-origin

Frequently Asked Questions

Is Citrus Grandis Leaf Extract safe in cosmetics?

EU Annex III restricted due to furocoumarin content. Verify furocoumarin levels and pesticide residue status for leaf-derived botanicals. Fragrance allergen labeling required if limonene/linalool/citral exceed declaration thresholds (0.001% rinse-off; 0.01% leave-on per EU Reg. 1223/2009 Annex III). The EU classifies Citrus Grandis Leaf Extract as "restricted". Safety rating: GOOD.

Is Citrus Grandis Leaf Extract allowed in the EU?

Citrus Grandis Leaf Extract EU regulatory status: restricted. Maximum allowed concentration: 0.506%. This is based on EU Regulation 1223/2009 and its amendments.

What does Citrus Grandis Leaf Extract do in cosmetics?

Citrus Grandis Leaf Extract functions as: Astringent; fragrance; skin conditioning; tonic. It is classified as a cosmetic ingredient in our database. CAS number: 90045-43-5 / 8016-20-4.

What is the Margin of Safety for Citrus Grandis Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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