Is COLLOIDAL SULFUR safe in cosmetics?
COLLOIDAL SULFUR has a safety rating of "GOOD" in our database. EU status: permitted. 1 toxicological study endpoint(s) are available in our database.
COLLOIDAL SULFUR
Also known as: Aquilite, Caswell No. 812, Colloidal-S, Collokit, Corosul D and S (+15 more)
COLLOIDAL SULFUR (CAS 7704-34-9) is a cosmetic cosmetic ingredient functioning as Antimicrobial. NOAEL 200 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Function
Antimicrobial
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
1 study endpoint found for COLLOIDAL SULFUR. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =400 mg/kg bw/day | dermal | Rat | short-term | ECHA |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Inhalation of the powder may cause inflammation of the nose and respiratory tract.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the respiratory tract. This may result in chronic bronchitis.
Routes of Exposure
The substance can be absorbed into the body by inhalation and by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for COLLOIDAL SULFUR across SCCS product categories, with measured dermal absorption where available.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Warning
Pictograms
Harmful / Irritant
Hazard Class and Category
Skin Irrit. 2
Hazard Statements
- H315 Causes skin irritation
Inserted via ATP: ATP22
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000,000 - 10,000,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | restricted | 5 (anti-dandruff) / 10 (anti-acne) | a) Anti-dandruff: 5%; b) Anti-acne: 10%; external use only |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Alloying element
Anti-dandruff
Anti-static agent
Binder
Biocide
Catalyst
Chemical reaction regulator
Degradant/impurity
Hardener
No specific technical function
Regulatory List Membership (2)
EU Regulated in Personal Care
FDA Indirect Food Contact Additives
Editorial summary
Preliminary editorial summary for COLLOIDAL SULFUR — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
cosing-sourced
eu-permitted
preservative
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to COLLOIDAL SULFUR by CAS number or substance name.
Studies
1
Lowest NOAEL
400 mg/kg bw/day
Highest NOAEL
400 mg/kg bw/day
ECHA
Known Synonyms
Aquilite
Caswell No. 812
Colloidal-S
Collokit
Corosul D and S
EINECS 231-722-6
EPA Pesticide Chemical Code 077501
Flour sulphur
Ground vocle sulfur
Kolloidschwefel 95
Kolofog
Kolospray
Kristex
Magnetic 70, 90, and 95
Microflotox
Netzschwefel
NSC 403664
Polsulkol extra
Rc-schwefel extra
Sperlox-S
Chemical Function
Biocide
Anti-static agent
Softener and conditioner
Pharmaceutical
Anti-dandruff
Regulatory Lists
detected; Europe; Home maintenance - caulk/sealant
active_ingredient; Pesticides
active_ingredient; agricultural; applied; Pesticides
active_ingredient; agricultural; applied; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
SULFUR
ChEMBL ID
CHEMBL1235452
Max Phase
4
Adverse Event Associations
105
Frequently Asked Questions
Is COLLOIDAL SULFUR allowed in the EU?
COLLOIDAL SULFUR EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does COLLOIDAL SULFUR do in cosmetics?
COLLOIDAL SULFUR functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 7704-34-9.
What is the NOAEL for COLLOIDAL SULFUR?
The NOAEL (No Observed Adverse Effect Level) for COLLOIDAL SULFUR is =400 mg/kg bw/day based on a short-term study via dermal route in Rat. Source: ECHA.
Is COLLOIDAL SULFUR used outside cosmetics?
COLLOIDAL SULFUR also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check COLLOIDAL SULFUR compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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