Good Cosmetic Ingredient NOAEL Data GHS Classified

COLLOIDAL SULFUR

CAS Number
7704-34-9
Function
Antimicrobial
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status Permitted
🇺🇸 US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

9 study endpoints found for COLLOIDAL SULFUR. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 400 mg/kg bw/day dermal rat dermal REACH
NOAEL 1000 other oral rat oral REACH
NOAEL 1000 other oral rat oral REACH
LOEL 9.3 mg/kg bw/day oral rat oral REACH
LOEL 80 other oral guinea pig oral REACH
NOAEL 200 mg/kg bw/day oral guinea pig oral REACH
NOAEL 120 mg/kg bw/day dermal cat dermal REACH
LOAEL 120 other oral guinea pig oral REACH
NOAEL 40 other oral guinea pig oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Inhalation of the powder may cause inflammation of the nose and respiratory tract.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the respiratory tract. This may result in chronic bronchitis.
Routes of Exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Expert Verdict

COLLOIDAL SULFUR is listed in the EU CosIng database with functions: Antimicrobial It is permitted in the EU without specific restrictions.

⚠️
Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted preservative needs-enrichment

Frequently Asked Questions

Is COLLOIDAL SULFUR safe in cosmetics?

COLLOIDAL SULFUR is listed in the EU CosIng database with functions: Antimicrobial It is permitted in the EU without specific restrictions. The EU classifies COLLOIDAL SULFUR as "Permitted". Safety rating: GOOD. 9 toxicological study endpoint(s) are available in our database.

Is COLLOIDAL SULFUR allowed in the EU?

COLLOIDAL SULFUR EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does COLLOIDAL SULFUR do in cosmetics?

COLLOIDAL SULFUR functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 7704-34-9.

What is the NOAEL for COLLOIDAL SULFUR?

The NOAEL (No Observed Adverse Effect Level) for COLLOIDAL SULFUR is 400 mg/kg bw/day based on a dermal study via dermal route in rat. A total of 9 study endpoints are available. Source: REACH.

Compliance Tools

Check COLLOIDAL SULFUR compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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