Copper Picolinate

INCI: COPPER PICOLINATE

CAS Number
27744-35-0
Function
Oral Care, Soothing
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA โ€” no specific cosmetic restriction. Picolinate salts (e.g., chromium picolinate, zinc picolinate) are widely used in dietary supplements and have some oral safety data.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Primary function is oral care; use in leave-on dermal products requires separate safety justification. No published dermal irritation/sensitization data. Copper picolinate's higher bioavailability versus other chelates may be a concern at higher concentrations.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Copper Picolinate safe in cosmetics?

Primary function is oral care; use in leave-on dermal products requires separate safety justification. No published dermal irritation/sensitization data. Copper picolinate's higher bioavailability versus other chelates may be a concern at higher concentrations. The EU classifies Copper Picolinate as "permitted". Safety rating: MODERATE.

Is Copper Picolinate allowed in the EU?

Copper Picolinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Copper Picolinate do in cosmetics?

Copper Picolinate functions as: Oral Care, Soothing. It is classified as a cosmetic ingredient in our database. CAS number: 27744-35-0.

What is the Margin of Safety for Copper Picolinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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